Laetrile and Cancer Treatment
In the 1950s, Dr. Ernst T. Krebs, Jr. began promoting laetrile as a treatment for cancer. He hypothesized that cancer cells could be targeted by cyanide released from amygdalin, leading to their destruction while leaving healthy cells unharmed. Laetrile was touted as a “natural” alternative to conventional treatments and gained popularity in alternative medicine circles.
Mechanisms of Action
How Does Vitamin B17 Work?
The proposed mechanism of action for Vitamin B17 in cancer treatment revolves around its ability to release cyanide in the presence of the enzyme beta-glucosidase, which is said to be more abundant in cancer cells. The theory suggests that when amygdalin is metabolized, cyanide is released selectively in cancerous tissues, leading to cell death while sparing healthy tissues.
Controversy Over Efficacy
Despite the theoretical framework supporting Vitamin B17, rigorous scientific studies have failed to demonstrate its efficacy as a cancer treatment. The National Cancer Institute (NCI) and other health organizations have conducted trials, consistently finding no significant benefit in using amygdalin or laetrile for cancer therapy.
Sources of Vitamin B17
Natural Food Sources
Vitamin B17 is primarily found in the seeds and pits of various fruits, including:
- Apricots: The most well-known source, apricot kernels are often marketed as a natural health product.
- Bitter Almonds: These contain higher concentrations of amygdalin compared to sweet almonds.
- Cherries and Peaches: The pits of these fruits also contain amygdalin.
Supplements and Laetrile
Laetrile is available as a dietary supplement, often marketed as a cancer remedy. However, it is essential to note that the quality and concentration of amygdalin in these supplements can vary significantly, and the safety and efficacy are not guaranteed.
Health Benefits and Risks
Potential Benefits
Some proponents of Vitamin B17 claim several health benefits, including:
- Anti-Cancer Properties: Advocates argue that amygdalin can help shrink tumors and improve overall health in cancer patients.
- Pain Relief: Some users report that laetrile can alleviate pain associated with cancer and its treatments.
- Immune System Support: There are claims that Vitamin B17 can enhance immune function, though scientific evidence is limited.
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